Feline Leukaemia Virus (FeLV)
The tamaVet® Feline Leukaemia Virus (FeLV) Test is intended for the rapid detection of feline leukaemia virus p27 (core protein) antigens in the whole blood, serum or plasma of cats. The feline leukaemia virus belongs to the Retroviridae family, and can be transmitted vertically or, more commonly, through direct contact. Once it has taken hold, the virus multiplies in four stages, beginning in the local lymphatic tissue and progressing to viraemia. In addition to multiplication in the spleen, lymph nodes and lymphatic tissue, it can also multiply in the bone marrow and epithelial cells, or even result in persistent viraemia. In the case of a regressive infection, the immune system is able to overcome the infection – however, the cat remains infected and in some cases resistance can develop. In the case of persistent viraemia, progressive infection can
result in illness. The primary symptoms include tumours (such as lymphosarcomas, thymus or intestinal leukosis), neuropathies and reproductive disorders. Degenerative and immunosuppressive effects facilitate the onset of FeLV-associated diseases, the symptoms of which vary greatly. Chronic rhinitis or gingivitis, the slowed healing of wounds, pyodermia and a susceptibility to infections are all typical. The p27 antigen is produced during the early viraemic phase, approximately 14 to 30 days after infection, as well as during all subsequent stages. The test is suitable for the rapid detection of feline leukaemia virus p27 antigens in the case of suspected infection or in the case of clinical symptoms, as well as for testing animals with an unknown immunisation status. If necessary, repeating the test is recommended.